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Ambassadors in Action - How do PCR's Work?

By Catherine Heath


I am a researcher working at The University of Edinburgh, and I ran a virtual session for higher biology pupils about how PCR is used to test people for the SARS-CoV-2 virus. I had been working in an NHS COVID-19 testing lab whilst I couldn’t do my regular job, and had also been helping to build a University wide testing scheme (TestEd). I wanted to use my relevant experience to demonstrate how something students are learning about in school directly relates to what scientists do in the real world, especially when tackling a pandemic.


I focused on how PCR works, building upon what the students had already covered, and how the technique can be applied to test for SARS-CoV-2 and its different variants. I talked briefly about the genome of the SARS-CoV-2 virus and used images from the lab of real positive and negative test samples to demonstrate the differences we were looking for.



Reading PCR results

I also tried to build in information about life as a scientist and a researcher to give pupils some insight into potential career options in STEM.


As the activity was run virtually, it was hard to gauge the immediate impact on the pupils as I had no face-to-face contact with them. The session was recorded so it could be used for other classes, which will extend the reach of the session. I hope this activity has helped the students think about real-world applications of the molecular biology techniques they are learning about, and potentially inspire them to go into a career in STEM.


I enjoyed thinking about my work in the larger context of the pandemic and making it relatable to the students. I would certainly do it again! If I had the opportunity to do it in person, I would like to do a more hands-on PCR based activity, such as a cut-and-stick exercise or even get the students to look at their own DNA if I could bring some equipment.

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The UK-wide STEM Ambassador programme is managed by STEM Learning Limited, which operates the National STEM Learning Network, alongside other projects supporting STEM education. To find out more please go to the STEM Learning website

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